HPE ProLiant DL380 Gen10: CPU, RAM, HDD/RAID Compatibility

Note: The information below is based on extensive in-house research and hands-on testing conducted by our expert technicians.

This guide provides detailed compatibility information and troubleshooting tips on CPU, RAM, and HDD/RAID options for the HPE ProLiant DL380 Gen10 to help optimise your system's performance and reliability.

HPE ProLiant DL380 Gen10 Specs: CPU, RAM HDD, RAID

CPU Generation 1st/2nd Gen Intel Scalable
CPU Quantity 2
Max CPU TDP N/A
CPU 2 Dependency Riser 2 + 3
Max DIMM Qty Total 24 PC4 R
Max RAM Frequency G1 CPU - 2666MHz
G2 CPU - 2933MHz
Max No. Single Slot GPUs 4 x PCIe 3.0 x16
Max No. Dual Slot GPUs 2 x PCIe 3.0 x16
Max GPU Length 10.5", 26.7cm
GPU Cable Length 10", 25.4cm
MB Power Connectors
(EPS/PCIe(6/8)/Proprietary)
1 per riser x Proprietary 8 pin
Onboard RAID Support
(SATA/SAS/NVMe)
SATA - up to 12 drives in RAID
NVMe (No RAID)
Onboard 4Kn HDD Support None
Add In Card 4Kn HDD Support MR Series cards only
Generic PCIe M.2 Adapter Boot Yes
Backplane U.2 Boot Yes

CPU COMPATIBILITY

How to upgrade HPE ProLiant DL380 Gen10 CPUs

The HPE ProLiant DL380 Gen10 supports the 1st and 2nd Generation Intel Xeon Scalable Processor Family. CPUs with a TDP of 130W or higher, such as the 8256, 8156, 6128, 5222, and 5122 models, require the high-performance heatsink for optimal cooling.

Processor Model TDP Additional Requirements
Intel Xeon 8256 130W High-performance heatsink required
Intel Xeon 8156 130W High-performance heatsink required
Intel Xeon 6128 130W High-performance heatsink required
Intel Xeon 5222 105W High-performance heatsink required
Intel Xeon 5122 105W High-performance heatsink required

For other CPU models supported by the HPE ProLiant DL380 Gen10, please refer to the official HPE documentation or consult with an HPE-certified technician.


Visit the DL380 Gen10 configurator for compatible CPUs.

RAM COMPATIBILITY

How to upgrade HPE ProLiant DL380 Gen10 RAM/Memory

The HPE ProLiant DL380 Gen10 supports DDR4 SmartMemory, offering high capacity and optimal performance when correctly configured. Below is the recommended DIMM population order for optimal performance when utilising up to 12 DIMM slots per CPU:

DIMMs Slot 1 Slot 2 Slot 3 Slot 4 Slot 5 Slot 6 Slot 7 Slot 8 Slot 9 Slot 10 Slot 11 Slot 12
1 DIMM 8
2 DIMMs 8 10
3 DIMMs 8 10 12
4 DIMMs 3 5 8 10
5 DIMMs* 3 5 8 10 12
6 DIMMs 1 3 5 8 10 12
7 DIMMs* 1 3 5 7 8 10 12
8 DIMMs 3 4 5 6 7 8 9 10
9 DIMMs* 1 3 5 7 8 9 10 11 12
10 DIMMs* 1 3 4 5 6 7 8 9 10 12
11 DIMMs* 1 3 4 5 6 7 8 9 10 11 12
12 DIMMs 1 2 3 4 5 6 7 8 9 10 11 12

*Unbalanced

Type: HPE DDR4 SmartMemory, Registered (RDIMM), Load Reduced (LRDIMM)
DIMM Slots Available: 24
Configuration: 12 DIMM slots per processor, 6 channels per processor, 2 DIMMs per channel

Maximum Capacity:
Note: All RAM speeds are dependent on the generation of CPU installed. G1 Scalable CPUs are limited to 2666MHz.

LRDIMM:
• 3.0 TB
• 24 x 128 GB LRDIMM @ 2933 MT/s

RDIMM:
• 1.54 TB
• 24 x 64 GB RDIMM @ 2933 MT/s

Intel Optane Persistent Memory for HPE:
• 6.0 TB
• 12 x 512 GB Memory Modules @ 2666 MT/s

HPE NVDIMMs:
• 192 GB
• 12 x 16 GB NVDIMM @ 2666 MT/s


Visit the DL380 Gen10 configurator for compatible memory modules.

HDD/RAID COMPATIBILITY

How to upgrade HPE ProLiant DL380 Gen10 Storage

The HPE ProLiant DL380 Gen10 offers various configurations for internal storage, maximising performance and capacity. Below are the details on supported drives:

Drive Capacity Configuration
Hot Plug SFF SAS HDD 72.0 TB 24+6 x 2.4 TB* (with optional rear SFF drive cage)
Hot Plug SFF SATA HDD 60.0 TB 24+6 x 2 TB (with optional SFF drive cage)
Hot Plug LFF SAS HDD 311.68 TB 12+4+3 x 16 TB + 2 x 3.84 TB (with optional mid-tray and rear LFF drive cage, plus 2 SFF SSD rear)
Hot Plug LFF SATA HDD 311.68 TB 12+4+3 x 16 TB + 2 x 3.84 TB (with optional mid-tray and rear LFF drive cage, plus 2 SFF SSD rear)
Hot Plug SFF SAS SSD 459 TB 24+6 x 15.3 TB (with optional rear SFF drive cage)
Hot Plug SFF SATA SSD 230.4 TB 24+6 x 7.68 TB (with optional rear SFF drive cage)
Hot Plug LFF SATA SSD 44.16 TB 12+4+3 x 1.92 TB + 2 x 3.84 TB (with optional mid-tray and rear LFF drive cage, plus 2 SFF SSD rear)
Hot Plug LFF SAS SSD 44.16 TB 12+4+3 x 1.92 TB + 2 x 3.84 TB (with optional mid-tray and rear LFF drive cage, plus 2 SFF SSD rear)
Hot Plug SFF NVMe PCIe SSD 307.2 TB 20 x 15.36 TB NVMe

Notes:

2x M.2 drives are supported on the Primary Riser.

UFF drives are also supported.


Visit the DL380 Gen10 configurator for compatible drives.

Internal Storage Devices

Depending on the model, the following internal storage devices are available:

  • Optical Drive
    Ships standard in Performance Models
    Optional: DVD-ROM, DVD-RW
  • Hard Drives
    None ship standard

RAID Controller Information

HPE Smart Array S100i SR Gen10 SW RAID

  • The S100i uses 14 embedded SATA ports, but only 12 ports are accessible as 2 are leveraged to support the 2 M.2 options on the primary riser.
  • If more than 8 SATA devices are being supported on this controller, then a SAS 3POS Cable Kit (826709-B21) is required.

Essential RAID Controllers:

  • HPE Smart Array E208i-a SR Gen10 Controller
  • HPE Smart Array E208i-p SR Gen10 Controller
  • HPE Smart Array E208e-p SR Gen10 Controller

Performance RAID Controllers:

  • HPE Smart Array P408i-a SR Gen10 Controller
  • HPE Smart Array P408i-p SR Gen10 Controller
  • HPE Smart Array P408e-p SR Gen10 Controller
  • HPE Smart Array P816i-a SR Gen10 Controller

Notes:

Performance RAID Controllers require the HPE U.2 Drives configured using the onboard S100i controller will not support any Hardware RAID without the addition of a RAID Card.


Configure your HPE ProLiant DL380 Gen10 server online now.

Categories: Knowledge Base HP HPE ProLiant DL380 Gen10 Articles